γ-Glutamyl Transpeptidase in Lactating Mammary Secretory Tissue of Cow and Rat
نویسندگان
چکیده
منابع مشابه
Monoclonal antibodies against rat kidney gamma-glutamyl transpeptidase show species and tissue specificity.
Monoclonal antibodies have been raised against rat kidney gamma-glutamyl transpeptidase (GGT). All five antibodies immunoprecipitate enzyme activity from solubilized kidney brush-border membranes, but not from hepatocellular carcinoma membranes. Three of the antibodies react immunohistochemically with brush-border membranes in sections of adult rat kidney, but none of the antibodies cross-react...
متن کاملFluctuations of Γ-glutamyl Transpeptidase in Normal and Cataractous Human Eye
The most common form of cataract is the “Senile Cataract” occurring in the aged population, which has great socio-medical prevalence for many third world countries, where annually 2-3 million people become blind due to cataract. The cause and phenomenon of cataract development may be same but the changes related with γglutamyl transpeptidase (GTP) activity depends on age and types of cataract. ...
متن کاملExpression and regulation of γ-glutamyl transpeptidase-related enzyme in tracheal cells.
Glutathione plays an essential role in protecting the pulmonary system from toxic insults. γ-Glutamyl transpeptidase-related enzyme (GGT-rel) is a novel protein capable of cleaving the γ-glutamyl peptide bond of glutathione and of converting leukotriene C4 to leukotriene D4. A rat homologue of GGT-rel was identified and was found to be highly expressed in cultures of differentiating rat trachea...
متن کاملInstrumental Role of Helicobacter pylori γ-Glutamyl Transpeptidase in VacA-Dependent Vacuolation in Gastric Epithelial Cells
Helicobacter pylori causes cellular vacuolation in host cells, a cytotoxic event attributed to vacuolating cytotoxin (VacA) and the presence of permeant weak bases such as ammonia. We report here the role of γ-glutamyl transpeptidase (GGT), a constitutively expressed secretory enzyme of H. pylori, in potentiating VacA-dependent vacuolation formation in H. pylori-infected AGS and primary gastric...
متن کاملGama-Glutamyl Transpeptidase and Glutathione Function
γ-Glutamyl transpeptidase (5-L-glutamyl-peptide: amino acid 5-glutamyl transferase; EC 2.3.2.2; abbreviated GGT), is a plasma membrane-associated enzyme that is located on the outer surface of the cells of secretory tissues [1]. It plays a central role in the metabolism of glutathione that is widely in various mammals [2]. The enzyme catalyzes the degradation of the extracellular glutathione in...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Dairy Science
سال: 1978
ISSN: 0022-0302
DOI: 10.3168/jds.s0022-0302(78)83599-1